milnacipran (cont.)

What is milnacipran (Savella)?
What are the possible side effects of milnacipran (Savella)?
What is the most important information I should know about milnacipran (Savella)?
What should I discuss with my healthcare provider before taking milnacipran (Savella)?
How should I take milnacipran (Savella)?
What happens if I miss a dose (Savella)?
What happens if I overdose (Savella)?
What should I avoid while taking milnacipran (Savella)?
What other drugs will affect milnacipran (Savella)?
Where can I get more information?

What happens if I miss a dose (Savella)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Savella)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include extreme drowsiness, slow heart rate, weak pulse, fainting, and slow breathing (breathing may stop).

What should I avoid while taking milnacipran (Savella)?

Avoid drinking alcohol. It may increase your risk of liver damage.

Milnacipran may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What other drugs will affect milnacipran (Savella)?

Before using milnacipran, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by milnacipran.

Ask your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with milnacipran may cause you to bruise or bleed easily.

Tell your doctor about all other medications you use, especially:

a blood thinner such as warfarin (Coumadin);
clonidine (Catapres, Clorpres);
a diuretic (water pill);
digoxin (digitalis, Lanoxin);
epinephrine (Epi-Pen);
lithium (Lithobid, Eskalith);
tramadol (Ultram);
tryptophan (sometimes called L-tryptophan);
medicine to treat a psychiatric disorder;
medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma);
migraine headache medicine such as almotriptan (Axert), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, Treximet), or zolmitriptan (Zomig); or
an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), desvenlafaxine (Pristiq), fluoxetine (Prozac, Sarafem, Symbyax), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).

This list is not complete and other drugs may interact with milnacipran. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about milnacipran.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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