What happens if I miss a dose (Lysodren)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Lysodren)?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a mitotane overdose are not known.

What should I avoid while taking mitotane (Lysodren)?

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of trauma or injury.

Mitotane can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What other drugs will affect mitotane (Lysodren)?

Before using mitotane, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by mitotane.

Tell your doctor about all other medications you use, especially:

• a blood thinner such as warfarin (Coumadin);
• spironolactone (Aldactone).

This list is not complete and there may be other drugs that can interact with mitotane. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about mitotane.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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