Medications and Drugs

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Brand Names: Embeda

Generic Name: morphine and naltrexone (Pronunciation: MOR feen and nal TREX one)

• What is morphine and naltrexone (Embeda)?
• What are the possible side effects of morphine and naltrexone (Embeda)?
• What is the most important information I should know about morphine and naltrexone (Embeda)?
• What should I discuss with my healthcare provider before using morphine and naltrexone (Embeda)?
• How should I use morphine and naltrexone (Embeda)?
• What happens if I miss a dose (Embeda)?
• What happens if I overdose (Embeda)?
• What should I avoid while using morphine and naltrexone (Embeda)?
• What other drugs will affect morphine and naltrexone (Embeda)?
• Where can I get more information?

What is morphine and naltrexone (Embeda)?

Morphine is in a group of drugs called narcotic pain relievers.

Naltrexone is a special narcotic drug that blocks the effects of other narcotic medicines and alcohol.

The combination of morphine and naltrexone is used to treat moderate to severe pain when around-the-clock pain relief is needed for a long time period.

Morphine and naltrexone is not for treating pain just after surgery unless you were already taking morphine and naltrexone before the surgery.

Morphine and naltrexone may also be used for other purposes not listed in this medication guide.

What are the possible side effects of morphine and naltrexone (Embeda)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; fast or pounding heartbeats, chest pain, difficulty breathing; dizziness, extreme fear; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• mood changes, hallucinations (seeing or hearing things), confusion;
• slow heart rate, weak pulse, fainting, weak or shallow breathing (breathing may stop);
• seizure (convulsions); or
• severe constipation or stomach pain.

Less serious side effects may include:

• drowsiness, dizziness, anxiety, tired feeling;
• nausea, vomiting, constipation, diarrhea;
• blurred vision, headache; or
• sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about morphine and naltrexone (Embeda)?

Do not use morphine and naltrexone if you have ever had an allergic reaction to a narcotic medicine, if you are having an asthma attack or if you have a bowel obstruction called paralytic ileus.

Before taking morphine and naltrexone, tell your doctor if you have a breathing disorder, liver or kidney disease, underactive thyroid, curvature of the spine, a history of head injury or brain tumor, gallbladder or pancreas disorders, a blockage in your stomach or intestines, Addison's disease, enlarged prostate, urination problems, a seizure disorder, a debilitating condition, mental illness, or a history of drug or alcohol addiction.

Do not drink alcohol while you are using morphine and naltrexone. Dangerous side effects or death can occur.

Never take more than your prescribed dose of morphine and naltrexone. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

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