What happens if I miss a dose (Orthoclone OKT3)?
Since muromonab-CD3 is given while you are in the hospital, it is unlikely that you will miss a dose.
What happens if I overdose (Orthoclone OKT3)?
An overdose of muromonab-CD3 is not expected to produce life-threatening symptoms.
What should I avoid while receiving muromonab-CD3 (Orthoclone OKT3)?
Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.
Avoid receiving a vaccine or flu shot shortly after you have been treated with muromonab-CD3, unless your doctor has told you to.
What other drugs will affect muromonab-CD3 (Orthoclone OKT3)?
Before receiving muromonab-CD3, tell your doctor if you are using any drugs that weaken your immune system, such as:
- cyclosporine (Neoral, Sandimmune, Gengraf);
- basiliximab (Simulect), efalizumab (Raptiva);
- azathioprine (Imuran), leflunomide (Arava), etanercept (Enbrel);
- steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;
- sirolimus (Rapamune), tacrolimus (Prograf);
- mycophenolate mofetil (CellCept);
- azathioprine (Imuran), leflunomide (Arava), etanercept (Enbrel); or
- any type of chemotherapy or radiation treatment.
This list is not complete and there may be other drugs that can interact with muromonab-CD3. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about muromonab-CD3.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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