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Medications and Drugs

Brand Names: Nubain

Generic Name: nalbuphine (Pronunciation: NAL bue feen)

What is nalbuphine (Nubain)?

Nalbuphine is an opioid pain medication. An opioid is sometimes called a narcotic.

Nalbuphine is used to treat moderate to severe pain. It is also used for treating pain just after surgery or childbirth.

Nalbuphine may also be used for purposes not listed in this medication guide.

What are the possible side effects of nalbuphine (Nubain)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • weak or shallow breathing;
  • fast or slow heart rate;
  • cold, clammy skin;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe weakness or drowsiness; or
  • feeling like you might pass out.

Less serious side effects are more likely to occur, such as:

  • feeling nervous or restless;
  • depression;
  • strange dreams;
  • stomach pain, upset stomach;
  • bitter taste in your mouth;
  • skin itching or burning, mild rash;
  • blurred vision, slurred speech; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nalbuphine (Nubain)?

You should not use this medication if you are allergic to nalbuphine.

Before you receive nalbuphine, tell your doctor if you have asthma or other breathing problems, liver or kidney disease, a slow heart rate, severe infection, gallbladder disease, mental illness, a history of head injury or brain tumor, or if you have recently had a heart attack.

Nalbuphine may be habit forming. Tell your doctor if you have a history of drug abuse or addiction.

Using nalbuphine may cause unpleasant side effects if you are already using other similar medicines. Using narcotic medications together can also increase the side effects of these medications.

Before you receive nalbuphine, tell your doctor about all other pain medicines you have recently used.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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