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nalbuphine (cont.)

What should I discuss with my healthcare provider before I receive nalbuphine (Nubain)?

You should not use this medication if you are allergic to nalbuphine.

To make sure you can safely use nalbuphine, tell your doctor if you have any of these other conditions:

  • asthma, COPD (chronic obstructive pulmonary disease), or other breathing disorder;
  • liver or kidney disease;
  • a history of head injury or brain tumor;
  • a slow heart rate, or if you have recently had a heart attack;
  • a severe infection;
  • gallbladder disease; or
  • mental illness.

Nalbuphine may be habit forming. Tell your doctor if you have a history of drug abuse or addiction.

FDA pregnancy category B. Nalbuphine is not expected to harm an unborn baby during early pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Although this medication is sometimes used during labor and delivery, nalbuphine can cause serious side effects in the newborn when the mother has received this medication shortly before childbirth. Effects of nalbuphine in the newborn may include breathing problems, a slow heart rate, a blue-colored appearance, and weak or limp muscles. If you receive this medication during labor and delivery, your caregivers will watch your baby closely for any serious side effects of nalbuphine. These effects can usually be treated quickly in a hospital setting.

It is not known whether nalbuphine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is nalbuphine given (Nubain)?

Nalbuphine is injected under the skin, into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.

Nalbuphine is usually given every 3 to 6 hours as needed. Your doctor may occasionally change your dose to make sure you get the best results.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

You should not stop using nalbuphine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using nalbuphine.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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