Medications and Drugs

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Brand Names:

Generic Name: nefazodone (Pronunciation: ne FAZ oh done)

• What is nefazodone ()?
• What are the possible side effects of nefazodone ()?
• What is the most important information I should know about nefazodone ()?
• What should I discuss with my healthcare provider before taking nefazodone ()?
• How should I take nefazodone ()?
• What happens if I miss a dose ()?
• What happens if I overdose ()?
• What should I avoid while taking nefazodone ()?
• What other drugs will affect nefazodone ()?
• Where can I get more information?

What is nefazodone ()?

Nefazodone is an antidepressant. It is used to treat depression, including major depressive disorder.

Nefazodone is not chemically similar to other groups of antidepressants, such as selective serotonin reuptake inhibitors or "SSRIs", tricyclic antidepressants, or monoamine oxidase inhibitors or "MAOIs."

Nefazodone may also be used for other purposes not listed in this medication guide.

Nefazodone 100 mg

oval, peach, imprinted with LOGO 4332, 100

Nefazodone 100 mg-TEV

oblong, white, imprinted with 93, 1024

Nefazodone 150 mg

round, peach, imprinted with 150, LOGO 4333

Nefazodone 150 mg-TEV

oblong, peach, imprinted with 93, 7113

Nefazodone 200 mg

oval, peach, imprinted with 200, LOGO 4334

Nefazodone 200 mg-TEV

oblong, yellow, imprinted with 93, 1025

Nefazodone 250 mg

round, peach, imprinted with 250, LOGO 4335

Nefazodone 250 mg-TEV

oblong, white, imprinted with 93, 1026

Nefazodone 50 mg

oval, peach, imprinted with Logo 4343, 50

Nefazodone 50 mg-TEV

oblong, pink, imprinted with 93, 7178

Serzone 100 mg

hexagonal, white, imprinted with BMS 100, 32

Serzone 150 mg

hexagonal, pink, imprinted with BMS 150, 39

Serzone 200 mg

hexagonal, yellow, imprinted with BMS 200, 33

Serzone 250 mg

hexagonal, white, imprinted with BMS 250, 41

Serzone 50 mg

hexagonal, pink, imprinted with BMS 40, 31

What are the possible side effects of nefazodone ()?

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Stop taking nefazodone and call your doctor at once if you have a serious side effect such as:

• nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• confusion, hallucinations, unusual thoughts or behavior;
• seizure (convulsions);
• penis erection that is painful or lasts 4 hours or longer;
• fever, chills, body aches, flu symptoms; or
• feeling like you might pass out.

Less serious side effects may include:

• mild nausea, diarrhea, constipation;
• dizziness, drowsiness, weakness;
• sleep problems (insomnia);
• dry mouth, sore throat;
• vision problems;
• headache; or
• increased appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nefazodone ()?

Do not take nefazodone together with carbamazepine (Tegretol), cisapride (Propulsid), pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam).

There are many other medicines that can interact with nefazodone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.