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Brand Names: Adalat CC, Procardia, Procardia XL

Generic Name: nifedipine (Pronunciation: nye FEH dih peen)

What is nifedipine (Adalat CC, Procardia, Procardia XL)?

Nifedipine is in a class of drugs called calcium channel blockers. Nifedipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Nifedipine is used to lower hypertension (high blood pressure) and to treat angina (chest pain).

Nifedipine may also be used for purposes other than those listed in this medication guide.

Adalat CC 30 mg

round, pink, imprinted with ADALAT CC, 30

Adalat CC 60 mg

round, pink, imprinted with ADALAT CC, 60

Adalat CC 90 mg

round, brown, imprinted with ADALAT CC, 90

Afeditab 30 mg-WAT

round, brown, imprinted with ELN 30

Afeditab 60 mg-WAT

round, brown, imprinted with ELN 60

Nifediac CC 30 mg-TEV

round, yellow, imprinted with 30, B

Nifediac CC 60 mg-TEV

round, yellow, imprinted with 60, B

Nifedipine 10 mg-PUR

yellow, imprinted with R497

Nifedipine 20 mg-PUR

red, imprinted with R 530

Nifedipine XL 30 mg-MYL

round, pink, imprinted with M 475

Nifedipine XL 30 mg-TEV

round, pink, imprinted with ELN 30

Nifedipine XL 60 mg-MYL

round, pink, imprinted with M482

Nifedipine XL 60 mg-TEV

round, brown, imprinted with 60, B

Nifedipine XL 90 mg-MYL

round, pink, imprinted with M 495

Nifedipine XL 90 mg-TEV

round, yellow, imprinted with B, 90

Procardia 10 mg

orange, imprinted with PROCARDIA PFIZER 260

Procardia XL 30 mg

round, pink, imprinted with PROCARDIA XL 30

Procardia XL 60 mg

round, pink, imprinted with PROCARDIA XL 60

Procardia XL 90 mg

round, pink, imprinted with PROCARDIA XL 90

What are the possible side effects of nifedipine (Adalat CC, Procardia, Procardia XL)?

If you experience any of the following serious side effects, stop taking nifedipine and contact your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • unusually fast or slow heartbeats;
  • severe dizziness or fainting;
  • psychosis;
  • yellowing of the skin or eyes (jaundice); or
  • swelling of the legs or ankles.

Other, less serious side effects may be more likely to occur. Continue to take nifedipine and talk to your doctor if you experience

  • headache, fatigue, or tiredness;
  • flushing;
  • insomnia;
  • vivid or abnormal dreams;
  • nausea or constipation; or
  • increased urination.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nifedipine (Adalat CC, Procardia, Procardia XL)?

Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

Do not crush, chew, or break any form of nifedipine. Swallow the pills whole.

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

What should I discuss with my healthcare provider before taking nifedipine (Adalat CC, Procardia, Procardia XL)?

Before taking nifedipine, tell your doctor if you have

  • kidney disease;
  • liver disease;
  • another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.

You may not be able to take nifedipine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Nifedipine is in the FDA pregnancy category C. This means that it is not known whether nifedipine will be harmful to an unborn baby. Do not take nifedipine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Nifedipine passes into breast milk. Do not take nifedipine without first talking to your doctor if you are breast-feeding a baby.

If you are over 65 years of age, you may be more likely to experience side effects from nifedipine. Your doctor may prescribe a lower dose of this medication.

How should I take nifedipine (Adalat CC, Procardia, Procardia XL)?

Take nifedipine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Adalat CC should be taken on an empty stomach.

Do not crush, chew, or break any form of nifedipine. Swallow the pills whole.

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Occasionally, the Procardia XL tablet shell may be seen in the stool. This is not harmful. The medicine has been absorbed by the body and the tablet shell is designed to be eliminated in the stool.

Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

Store nifedipine at room temperature away from moisture and heat.

What happens if I miss a dose (Adalat CC, Procardia, Procardia XL)?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose (Adalat CC, Procardia, Procardia XL)?

Seek emergency medical attention.

Symptoms of a nifedipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

What should I avoid while taking nifedipine (Adalat CC, Procardia, Procardia XL)?

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Follow any recommendations your doctor makes about diet or exercise.

Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions.

Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking nifedipine.

What other drugs will affect nifedipine (Adalat CC, Procardia, Procardia XL)?

Before taking nifedipine, tell your doctor if you are taking any of the following drugs:

  • another heart medication to treat the same or another condition;
  • cimetidine (Tagamet, Tagamet HB);
  • erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);
  • itraconazole (Sporanox) or ketoconazole (Nizoral);
  • carbamazepine (Tegretol);
  • phenytoin (Dilantin); or
  • rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).

You may not be able to take nifedipine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with nifedipine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about nifedipine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medication for the condition prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2003 Cerner Multum, Inc. Version: 7.02. Revision date: 4/12/2009.

Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.

Healthwise

Last Updated: April 12, 2009


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