Medications and Drugs
Brand Names: Tasigna
Generic Name: nilotinib (Pronunciation: nye LOE ti nib)
What is nilotinib (Tasigna)?
Nilotinib interferes with the growth of some cancer cells.
Nilotinib is used to treat a type of blood cancer called Philadelphia chromosome positive chronic myeloid leukemia (CML).
Nilotinib may also be used for other purposes not listed in this medication guide.
What are the possible side effects of nilotinib (Tasigna)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using nilotinib and call your doctor at once if you have a serious side effect such as:
Less serious side effects may be more likely to occur, such as:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about nilotinib (Tasigna)?
You should not use nilotinib if you are allergic to it, or if you have low blood levels of potassium or magnesium, or a history of "Long QT syndrome."
You should not breast-feed while you are taking nilotinib.
Before using nilotinib, tell your doctor if you have heart disease or a heart rhythm disorder, liver disease, a personal history of pancreatitis, a family history of "Long QT syndrome," or if your stomach has been surgically removed (total gastrectomy).
You will need regular medical tests to be sure this medication is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.
Call your doctor at once if you have a serious side effect such as feeling light-headed with a fast or pounding heartbeat, pale skin, easy bruising or bleeding, fever, flu symptoms, cough with stabbing chest pain, mouth sores, feeling light-headed or short of breath, swelling, sudden headache or vision problems, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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