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nilotinib (cont.)

What should I discuss with my healthcare provider before taking nilotinib (Tasigna)?

You should not use nilotinib if you are allergic to it, or if you have:

  • low blood levels of potassium or magnesium; or
  • a history of long QT syndrome.

To make sure nilotinib is safe for you, tell your doctor if you have any of these conditions:

  • heart disease;
  • a personal or family history of Long QT syndrome;
  • liver disease;
  • a personal history of pancreatitis; or
  • if your stomach has been surgically removed (total gastrectomy).

FDA pregnancy category D. Do not use nilotinib if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether nilotinib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking nilotinib.

Nilotinib capsules may contain lactose. Talk to your doctor before using this medication if you have galactose intolerance, or severe problems with lactose (milk sugar).

How should I take nilotinib (Tasigna)?

Nilotinib is usually taken every 12 hours. Follow the directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take nilotinib on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not take with food.

Take this medicine with a full glass of water.

Swallow the nilotinib capsule whole.

To make swallowing easier, you may open the nilotinib capsule and sprinkle the medicine into 1 teaspoon of applesauce. Swallow right away without chewing. Do not save the mixture for later use.

You will need frequent medical tests at your doctor's office to be sure this medication is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests.

Do not stop using nilotinib or change your dose without talking to your doctor. If you stop taking the medication too soon, your condition may get worse.

Store at room temperature away from moisture and heat.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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