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nilotinib (cont.)

IN THIS ARTICLE

What happens if I miss a dose (Tasigna)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Tasigna)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness and vomiting.

What should I avoid while taking nilotinib (Tasigna)?

Do not take with food. Food can increase your blood levels of nilotinib and may increase your risk of harmful side effects.

Grapefruit and grapefruit juice may interact with nilotinib and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.

Avoid taking an antacid within several hours before or after you take nilotinib.

What other drugs will affect nilotinib (Tasigna)?

Many drugs can interact with nilotinib and not all possible interactions are listed in this medication guide. Tell your doctor about all medications you use, and those you start or stop using during your treatment with nilotinib, especially:

  • esomeprazole (Nexium) and other stomach acid reducers;
  • ergotamine (Ergomar, Cafergot) or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray);
  • St. John's wort;
  • theophylline (Aquaphyllin, Asmalix, Elixophyllin, Theolair, Theosol);
  • a blood thinner or medication to prevent blood clots;
  • an antibiotic, or tuberculosis medicine;
  • antifungal medication;
  • anti-malaria medication;
  • cancer medication, an immunosuppressant, or medicine to prevent organ transplant rejection;
  • heart or blood pressure medication, heart rhythm medication;
  • medications to treat HIV, AIDS, or hepatitis C;
  • medicine to treat depression or mental illness;
  • medicine to treat or prevent nausea;
  • narcotic pain medication, a sedative, or a medication to treat narcolepsy;
  • seizure medication; or
  • steroid medication.

This list is not complete and many other drugs can interact with nilotinib. This includes prescription, over-the-counter, vitamin, and herbal products. Give a list of all your medicines to any healthcare provider who treats you

Where can I get more information?

Your pharmacist can provide more information about nilotinib.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 11.01. Revision date: 11/15/2012.

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