What happens if I miss a dose (Tasigna)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Tasigna)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose may cause drowsiness or vomiting.
What should I avoid while taking nilotinib (Tasigna)?
Do not take with food. Food can increase your blood levels of nilotinib and may increase your risk of harmful side effects.
Grapefruit and grapefruit juice may interact with nilotinib and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect nilotinib (Tasigna)?
Many drugs can interact with nilotinib. Below is just a partial list. Tell your doctor if you are using:
- arsenic trioxide (Trisenox);
- conivaptan (Vaprisol);
- droperidol (Inapsine);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- midazolam (Versed);
- pimozide (Orap);
- St. John's wort;
- a blood thinner such as warfarin (Coumadin, Jantoven);
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), moxifloxacin (Avelox), telithromycin (Ketek), and others;
- antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
- an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), desipramine (Norpramin), or nefazodone;
- anti-malaria medications such as chloroquine (Arelan), halofantrine (Halfan), or mefloquine (Lariam);
- heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), diltiazem (Cartia, Cardizem), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), felodipine (Plendil), ibutilide (Corvert), nicardipine (Cardene), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace);
- HIV/AIDS medicine such as delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Kaletra, Norvir), and others;
- medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
- medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);
- medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);
- migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);
- narcotic medication such as methadone (Methadose, Diskets, Dolophine); or
- stomach acid reducers such as dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (Aciphex).
Where can I get more information?
Your pharmacist can provide more information about nilotinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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