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Medications and Drugs

Brand Names: Zegerid, Zegerid OTC

Generic Name: omeprazole and sodium bicarbonate (Pronunciation: oh ME pray zol and SO dee um by KAR bon ate)

What is omeprazole and sodium bicarbonate (Zegerid, Zegerid OTC)?

Omeprazole is a proton pump inhibitor that decreases the amount of acid your stomach produces. Sodium bicarbonate is an antacid that raises the pH in your stomach to keep the omeprazole from breaking down in stomach acid.

Omeprazole and sodium bicarbonate is a combination medicine used to treat heartburn and other symptoms of gastroesophageal reflux disease (GERD). This medicine is also used to treat ulcers and other conditions involving excessive stomach acid production.

Omeprazole and sodium bicarbonate is not for immediate relief of heartburn symptoms.

Omeprazole and sodium bicarbonate may also be used for purposes not listed in this medication guide.

What are the possible side effects of omeprazole and sodium bicarbonate (Zegerid, Zegerid OTC)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • stiffness or loss of movement in any part of your body;
  • diarrhea that is watery or bloody;
  • fast or slow heartbeats;
  • seizure (convulsions); or
  • low magnesium (dizziness, confusion, fast or uneven heart rate, jerking muscle movements, jittery feeling, muscle cramps, muscle weakness or limp feeling, cough or choking feeling).

Common side effects may include:

  • headache;
  • nausea, stomach pain, gas; or
  • mild diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about omeprazole and sodium bicarbonate (Zegerid, Zegerid OTC)?

Omeprazole and sodium bicarbonate is a combination medicine used to treat heartburn and other symptoms of gastroesophageal reflux disease (GERD). This medicine is also used to treat ulcers and other conditions involving excessive stomach acid production. Symptom relief does not mean that serious stomach problems (like cancer) do not exist. Talk to your doctor if old stomach symptoms return or new symptoms appear.

This medication contains sodium bicarbonate, a form of salt. If you are on a low-salt or low-sodium diet, you may not be able to use omeprazole and sodium bicarbonate. Talk with your doctor.

This medication can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking omeprazole and sodium bicarbonate and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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