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What happens if I miss a dose (Zofran)?

Call your doctor for instructions.

What happens if I overdose (Zofran)?

Seek emergency medical attention if you think you have received too much of this medicine.

Symptoms of an ondansetron overdose may include sudden loss of vision, severe constipation, feeling light-headed, fainting.

What should I avoid while receiving ondansetron injection (Zofran)?

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by ondansetron injection.

Ondansetron injection can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What other drugs will affect ondansetron injection (Zofran)?

Before receiving ondansetron injection, tell your doctor if you are using any of the following drugs:

• phenytoin (Dilantin), phenobarbital (Luminal);
• carbamazepine (Carbatrol, Tegretol);
• tramadol (Ultram);
• rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, Rifater);
• amiodarone (Cordarone), mibefradil (Posicor);
• cimetidine (Tagamet);
• clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab); or
• HIV medicines such as indinavir (Crixivan), saquinavir (Invirase), ritonavir (Norvir), or nelfinavir (Viracept).

If you are using any of these drugs, you may not be able to use ondansetron injection, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect ondansetron injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist has more information about ondansetron injection written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 1.05. Revision date: 12/15/2010.

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