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What should I discuss with my healthcare provider before receiving paclitaxel (Onxol)?
You should not be given this medication if you are allergic to paclitaxel, or to other medications that contain an ingredient called Cremophor EL (polyoxyethylated castor oil). This includes cyclosporine (Gengraf, Neoral, Sandimmune) and teniposide (Vumon).
To make sure you can safely take paclitaxel, tell your doctor if you have any of these other conditions:
It is not known whether paclitaxel passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using paclitaxel.
How is paclitaxel given (Onxol)?
Paclitaxel is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Paclitaxel must be given slowly, and the IV infusion can take up to 24 hours to complete.
Paclitaxel is usually given once every 3 weeks. Follow your doctor's dosing instructions very carefully.
You may be given other medications to prevent an allergic reaction while you are receiving paclitaxel.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving paclitaxel.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when paclitaxel is injected.
Paclitaxel can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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