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Medications and Drugs

Brand Names: Hi-Vegi-Lip, Pancreatin 4X

Generic Name: pancreatin (Pronunciation: PAN kree a tin)

What is pancreatin (Hi-Vegi-Lip, Pancreatin 4X)?

Pancreatin is a combination of digestive enzymes (proteins). These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars.

Pancreatin is used to replace digestive enzymes when the pancreas does not produce enough on its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, pancreatic cancer, or pancreas surgery.

Pancreatin may also be used to treat a condition called steatorrhea (loose, fatty stools).

Pancreatin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of pancreatin (Hi-Vegi-Lip, Pancreatin 4X)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • swollen or painful joints;
  • urinating more than usual; or
  • painful or difficult urination.

Less serious side effects may include:

  • mild stomach pain or cramps;
  • nausea, diarrhea, constipation;
  • greasy stools;
  • rectal irritation; or
  • bloating or gas.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about pancreatin (Hi-Vegi-Lip, Pancreatin 4X)?

Pancreatin is usually taken with meals and snacks and a full glass of water. Follow your doctor's instructions.

Do not hold the pancreatin tablet in your mouth. The medication may irritate the inside of your mouth.

Do not change brands of pancreatin without first talking to your doctor or pharmacist. Some brands of pancreatin are interchangeable while others are not. Ask your pharmacist which brands or generic forms can be substituted for another.

Pancreatin may be only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

Do not take pancreatin with other digestive enzymes that your doctor has not prescribed.

Call your doctor at once if you have a serious side effect such as swollen or painful joints, urinating more than usual, or painful or difficult urination.

If you miss a dose of this medication, skip the missed dose and wait until your next scheduled dose to take the medicine. Do not take extra medicine to make up the missed dose.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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