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What happens if I miss a dose (Oncaspar)?

Contact your doctor if you miss an appointment for your pegaspargase injection.

What happens if I overdose (Oncaspar)?

Seek emergency medical attention if you think you have received too much of this medicine. Symptoms of a pegaspargase overdose may include easy bruising or bleeding, unusual weakness, nausea, loss of appetite, and jaundice (yellowing of the skin or eyes).

What should I avoid while receiving pegaspargase (Oncaspar)?

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

What other drugs will affect pegaspargase (Oncaspar)?

Before receiving asparaginse, tell your doctor if you are using any of the following drugs:

• vincristine (Oncovin, Vincasar);
• prednisone (Deltasone, Meticorten, Orasone, and others); or
• methotrexate (Folex, Rheumatrex, Trexall).

If you are using any of these drugs, you may not be able to receive pegaspargase, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect pegaspargase. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about pegaspargase written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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