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What happens if I miss a dose (Nembutal Sodium)?

Since pentobarbital is often used only when needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Nembutal Sodium)?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of pentobarbital can be fatal.

Overdose symptoms may include pinpoint or dilated pupils, weak or limp feeling, urinating less than usual or not at all, fast heart rate, slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

What should I avoid while taking pentobarbital (Nembutal Sodium)?

Pentobarbital can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. Alcohol can add to sleepiness caused by pentobarbital, which could be dangerous.

What other drugs will affect pentobarbital (Nembutal Sodium)?

Before using pentobarbital, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can cause add to sleepiness caused by pentobarbital, which could be dangerous.

Tell your doctor about all other medications you use, especially:

• a blood thinner such as warfarin (Coumadin);
• doxycycline (Adoxa, Doryx, Mondox, Oracea, Vibramycin, and others);
• other seizure medications such as divalproex (Depakote), phenytoin (Dilantin), or valproic acid (Depakene);
• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
• griseofulvin (Grisactin, Fulvicin PG, Grifulvin V);
• birth control pills or hormone replacement estrogens; or
• steroids such as prednisone (Orasone, Deltasone), prednisolone (Prelone, Delta Cortef), methylprednisolone (Medrol), and others.

This is not a complete list and there may be other drugs that can interact with pentobarbital. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about pentobarbital.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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