Medications and Drugs
Brand Names: Elmiron
Generic Name: pentosan polysulfate sodium (Pronunciation: PEN toe san POL ee SUL fate SOE dee um)
What is pentosan polysulfate sodium (Elmiron)?
Pentosan polysulfate sodium works like an anticoagulant (blood thinner) that prevents the formation of blood clots. However, it is used to treat bladder pain and discomfort caused by cystitis (bladder inflammation or irritation).
Pentosan polysulfate sodium may also be used for purposes not listed in this medication guide.
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What are the possible side effects of pentosan polysulfate sodium (Elmiron)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about pentosan polysulfate sodium (Elmiron)?
Before taking pentosan polysulfate sodium, tell your doctor if you have a bleeding or blood clotting disorder, a history of aneurysm or stroke, a stomach ulcer, intestinal polyps, diverticulitis, or liver disease.
Take the medicine on an empty stomach, at least 1 hour before or 2 hours after a meal.
Call your doctor at once if you have any easy bruising or unusual bleeding such as nosebleed, blood in your urine or stools, rectal bleeding, coughing up blood, bleeding gums, or feeling like you might pass out.
To be sure this medication is helping your condition, your doctor will need to check your progress every 3 months. This will help your doctor determine how long to treat you with pentosan polysulfate sodium. You may also need blood tests to check for certain side effects. Visit your doctor regularly.
Tell your doctor if you use any other medications that can increase your risk of bleeding, including blood thinners, medications to treat or prevent blood clots, or an NSAID (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), indomethacin (Indocin), and others.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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