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What happens if I miss a dose (Nipent)?

Contact your doctor if you miss a dose of pentostatin injection.

What happens if I overdose (Nipent)?

If for any reason an overdose of pentostatin is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Symptoms of a pentostatin overdose tend to be similar to side effects caused by the medication, although often more severe.

What should I avoid while taking pentostatin (Nipent)?

Pentostatin can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with pentostatin. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

What other drugs will affect pentostatin (Nipent)?

Do not take pentostatin without first talking to your doctor if you are taking any of the following medications:

• fludarabine (Fludara);
• carmustine(BiCNU, others);
• etoposide(Etopophos, Toposar, Vepesid );
• cyclophosphamide(Cytoxan, Neosar); or
• vidarabine eye drops (Vira-A); or
• any other cancer (chemotherapy) medications.

You may not be able to take pentostatin, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Do not receive "live" vaccines during treatment with pentostatin. Administration of a live vaccine may be dangerous during treatment with pentostatin.

Drugs other than those listed here may also interact with pentostatin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about pentostatin written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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