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What happens if I miss a dose (Phenergan VC, Promethazine VC Plain)?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose (Phenergan VC, Promethazine VC Plain)?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a phenylephrine and promethazine overdose include severe drowsiness, dizziness, headache, seizures, dry mouth, large pupils, flushing, nausea, vomiting, difficulty breathing, and unconsciousness.

What should I avoid while taking phenylephrine and promethazine (Phenergan VC, Promethazine VC Plain)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phenylephrine and promethazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking phenylephrine and promethazine.

Avoid prolonged exposure to sunlight. Phenylephrine and promethazine may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Do not take other over-the-counter cough, cold, allergy, diet, pain, fever, or sleep medicines while taking phenylephrine and promethazine without first talking to your doctor or pharmacist. Other medications may also contain phenylephrine, promethazine or other similar drugs, and you may accidentally take too much, which could be harmful.

What other drugs will affect phenylephrine and promethazine (Phenergan VC, Promethazine VC Plain)?

Do not take phenylephrine and promethazine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), or selegiline (Eldepryl) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Phenylephrine and promethazine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Do not take other over-the-counter cough, cold, allergy, diet, pain, fever, or sleep medicines while taking phenylephrine and promethazine without first talking to your doctor or pharmacist. Other medications may also contain phenylephrine, promethazine or other similar drugs, and you may accidentally take too much, which could be harmful.

Drugs other than those listed here may also interact with phenylephrine and promethazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has more information about phenylephrine and promethazine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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