piperacillin and tazobactam (cont.)
What happens if I miss a dose (Zosyn)?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose (Zosyn)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe anxiety, agitation, feeling restless or nervous, or seizure (convulsions).
What should I avoid while using piperacillin and tazobactam (Zosyn)?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
What other drugs will affect piperacillin and tazobactam (Zosyn)?
Piperacillin and tazobactam may cause bleeding, especially in people with kidney disease or using certain medicines. Tell your doctor if you are using any medication to prevent blood clots, such as:
- abciximab (ReoPro);
- alteplase (Activase);
- anagrelide (Agrylin);
- argatroban (Acova);
- bivalirudin (Angiomax);
- cilostazol (Pletal);
- clopidogrel (Plavix);
- dipyridamole (Persantine);
- dabigatran (Pradaxa);
- dalteparin (Fragmin);
- dipyridamole (Persantine, Aggrenox);
- enoxaparin (Lovenox);
- eptifibatide (Integrelin);
- fondaparinux (Arixtra);
- lepirudin (Refludan);
- prasugrel (Effient);
- tenecteplase (TNKase);
- ticlopidine (Ticlid);
- tinzaparin (Innohep);
- tirofiban (Aggrastat);
- urokinase (Abbokinase); or
- warfarin (Coumadin, Jantoven).
Tell your doctor about all other medicines you use, especially:
This list is not complete and other drugs may interact with piperacillin and tazobactam. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about piperacillin and tazobactam.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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