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podophyllum resin (topical) (cont.)

What should I discuss with my health care provider before using podophyllum resin topical (Podocon-25)?

You should not use this medication if you are allergic to podophyllum resin topical.

Before using podophyllum resin topical, tell your doctor if you have:

  • diabetes;
  • circulation problems;
  • Raynaud's syndrome;
  • if you use steroid medications such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others; or
  • if you are pregnant or breast-feeding.

If you have any of these conditions, you may not be able to use podophyllum resin topical, or you may need a dose adjustment or special tests during treatment.

FDA pregnancy category X. This medication can cause birth defects. Do not use podophyllum resin topical if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medication.

It is not known whether podophyllum resin passes into breast milk or if it could harm a nursing baby. Do not use this medication if you are breast-feeding a baby.

How should I take podophyllum resin topical (Podocon-25)?

Use podophyllum resin topical exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Using more of the medication than prescribed will not make it work better, and may increase your risk of unpleasant side effects. Follow the directions on your prescription label.

Wash your hands before and after using this medication.

Apply the medication using the applicator provided, or using a clean cotton swab. You may need to use a hand mirror to guide you in applying the medicine directly to the wart. Throw away the applicator after one use. Do not reuse an applicator.

Apply podophyllum resin topical only to the wart and avoid getting it on the surrounding skin.

Allow the treated wart to dry completely before dressing or allowing treated skin to come into contact with healthy skin.

Do not use this medication to treat genital warts inside the rectum, vagina, or penis. It should only be applied to the outside (external) skin.

Do not apply podophyllum resin topical to warts or surrounding skin that is bleeding, swollen or irritated. Do not use on moles, birthmarks, or any wart your doctor has not instructed you to treat with podophyllum resin.

You may need to use podophyllum resin topical only on certain days of the week. It is important to use the medication regularly to get the most benefit. Follow your doctor's instructions.

Your doctor may want to check your progress at regular intervals while you are using this medication. Do not miss any scheduled appointments.

Store the medication at room temperature, away from moisture and heat.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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