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Medications and Drugs

Brand Names: Polytrim

Generic Name: polymyxin B and trimethoprim ophthalmic (Pronunciation: paw lee MIX in B and try METH oh prim)

What is polymyxin B and trimethoprim ophthalmic (Polytrim)?

Polymyxin B and trimethoprim are antibiotics that fight bacteria in the body.

Polymyxin B and trimethoprim ophthalmic (for the eye) is used to treat eye infections caused by bacteria.

Polymyxin B and trimethoprim ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of polymyxin B and trimethoprim ophthalmic (Polytrim)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • swelling or redness of your eyelids;
  • eye redness, pain, irritation or sensitivity to light; or
  • drainage, crusting, or oozing of your eyes or eyelids.

Less serious side effects may include:

  • mild burning, stinging, or itching in your eye;
  • mild swelling, itching, or redness of your eyelids;
  • blurred vision;
  • watery eyes; or
  • mild skin rash around your eyes.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about polymyxin B and trimethoprim ophthalmic (Polytrim)?

You should not use this medication if you are allergic to polymyxin B or trimethoprim.

Wash your hands before using the eye drops.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use this medication while you are wearing contact lenses. Polymyxin B and trimethoprim ophthalmic may contain a preservative that can be absorbed by soft contact lenses and cause discoloration. Wait at least 15 minutes after using polymyxin B and trimethoprim ophthalmic before putting your contact lenses in.

Stop using this medication and call your doctor at once if you have swelling or redness of your eyelids, eye redness, eye pain, sensitivity to light; or drainage, crusting, or oozing of your eyes or eyelids.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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