IN THIS ARTICLE
- What is pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- What are the possible side effects of pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- What is the most important information I should know about pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- What should I discuss with my doctor before using pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- How should I use pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- What happens if I miss a dose (Symlin, SymlinPen 120, SymlinPen 60)?
- What happens if I overdose (Symlin, SymlinPen 120, SymlinPen 60)?
- What should I avoid while using pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- What other drugs will affect pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
- Where can I get more information?
What happens if I miss a dose (Symlin, SymlinPen 120, SymlinPen 60)?
Take the missed dose as soon as you remember, but only if you are getting ready to eat a meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Symlin, SymlinPen 120, SymlinPen 60)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause diarrhea, vomiting, dizziness, cold sweats, warmth or tingly feeling.
What should I avoid while using pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
Do not remove pramlintide from an injector pen and put it in a syringe. You may receive too high a dose.
Avoid drinking alcohol. It can lower your blood sugar.
What other drugs will affect pramlintide (Symlin, SymlinPen 120, SymlinPen 60)?
The following drugs can interact with pramlintide. Tell your doctor if you are using any of these:
- acarbose (Precose) or miglitol (Glyset);
- disopyramide (Norpace);
- fluoxetine (Luvox);
- pentoxyfylline (Trental);
- propoxyphene (Darvon, Darovcet);
- diabetes medications you take by mouth;
- atropine (Atreza, Sal-Tropine), dicyclomine (Bentyl), hyoscyamine (Hyomax), oxybutynin (Ditropan, Oxytrol);
- an ACE inhibitor such as benazepril (Lotensin), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others; or
- cholesterol-lowering medication such as fenofibrate (Lofibra, Fenoglide, TriCor, Lipofen) or gemfibrozil (Lopid).
Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use any of the following:
- albuterol (Proventil, Ventolin);
- clonidine (Catapres); or
- a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.
You may be more likely to have high or low blood sugar if you are using pramlintide with other drugs that raise or lower blood sugar. This includes:
- probenecid (Benemid);
- aspirin or other salicylates (including Pepto-Bismol);
- birth control pills and other hormones;
- diet pills or medicines to treat asthma, colds or allergies;
- diuretics (water pills);
- a monoamine oxidase inhibitor (MAOI);
- phenothiazines (Compazine and others);
- steroids (prednisone and others);
- seizure medicines (Dilantin and others);
- some nonsteroidal anti-inflammatory drugs (NSAIDs); and
- sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others).
These lists are not complete and other drugs may interact with pramlintide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about pramlintide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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