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Medications and Drugs

Brand Names: Anusol, Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal

Generic Name: pramoxine and zinc oxide topical (Pronunciation: pra MOX een and ZINK OX ide TOP ik al)

What is pramoxine and zinc oxide topical (Anusol, Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal)?

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Zinc oxide is a mineral.

The combination of pramoxine and zinc oxide topical (for the skin) is used to treat itching, burning, irritation, or other rectal discomfort caused by hemorrhoids or painful bowel movements.

Pramoxine and zinc oxide topical may also be used for purposes not listed in this medication guide.

What are the possible side effects of pramoxine and zinc oxide topical (Anusol, Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using pramoxine and zinc oxide topical and call your doctor at once if you have a serious side effect such as:

  • any new redness or swelling where the medicine was applied;
  • severe pain, burning, or stinging where the medicine is applied; or
  • rectal bleeding or continued pain.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about pramoxine and zinc oxide topical (Anusol, Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal)?

You should not use this medication if you are allergic to pramoxine, zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Avoid getting this medicine in your eyes, nose, or vagina. If this does happen, rinse with water.

Pramoxine and zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing lesions around your rectum.

Stop using pramoxine and zinc oxide topical and call your doctor if your symptoms do not improve after 7 day of treatment, or if your condition clears up and then comes back.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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