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Medications and Drugs

Brand Names: Mysoline

Generic Name: primidone (Pronunciation: PRIM i done)

What is primidone (Mysoline)?

Primidone is an anti-epileptic drug, also called an anticonvulsant.

Primidone is used to control seizures.

Primidone may also be used for other purposes not listed in this medication guide.

Mysoline 50 mg

square, white, imprinted with LOGO, MYSOLINE 50, M

Primidone 250 mg-GLO

square, white, imprinted with C42

Primidone 250 mg-MUT

round, yellow, imprinted with MP 738

Primidone 250 mg-SCH

round, white, imprinted with DAN DAN, 5321

Primidone 250 mg-WAT

round, white, imprinted with 5321, DAN DAN

Primidone 50 mg-GLO

square, white, imprinted with C41

Primidone 50 mg-LAN

round, white, imprinted with LAN 1301

Primidone 50 mg-MUT

round, white, imprinted with MP 737

What are the possible side effects of primidone (Mysoline)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

  • slurred speech;
  • loss of balance or coordination;
  • easy bruising or bleeding; or
  • unusual weakness.

Less serious side effects may include:

  • dizziness, drowsiness, spinning sensation;
  • nausea, vomiting, loss of appetite;
  • feeling irritable;
  • blurred vision;
  • mild skin rash; or
  • impotence, loss of interest in sex.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about primidone (Mysoline)?

You should not use this medication if you are allergic to primidone or phenobarbital (Luminal, Solfoton), or if you have porphyria.

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you are pregnant or breast-feeding.

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

If you are taking primidone to prevent seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking primidone. Follow your doctor's instructions.

To be sure this medication is helping your condition, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.

Do not change your dose of primidone without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.

Carry an ID card or wear a medical alert bracelet stating that you are taking primidone, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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