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probenecid (cont.)

What should I discuss with my healthcare provider before taking probenecid (Benemid)?

You should not use this medication if you are allergic to probenecid, or if you have:

  • uric acid kidney stones;
  • a gout attack that has already started; or
  • a blood cell disorder such as anemia, or decreased white blood cells.

Before taking probenecid, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;
  • a history of stomach ulcer; or
  • if you have ever had kidney stones.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take probenecid.

Probenecid may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether probenecid passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Probenecid should not be given to a child younger than 2 years old.

How should I take probenecid (Benemid)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Drink plenty of water to prevent kidney stones while you are taking probenecid.

Probenecid may be only part of a complete program of treatment that also includes diet, other medications, and mineral supplements. Follow your doctor's instructions.

To be sure this medication is not causing harmful effects, your blood or urine may need to be tested on a regular basis. Do not miss any scheduled appointments.

If you are taking probenecid together with an antibiotic, be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking probenecid. This medication may affect your body's response to anesthesia.

Store probenecid at room temperature away from moisture and heat.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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