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Medications and Drugs

Brand Names: Rythmol, Rythmol SR

Generic Name: propafenone (Pronunciation: proe PAF e none)

What is propafenone (Rythmol, Rythmol SR)?

Propafenone is in a group of drugs called Class IC anti-arrhythmics. It affects the way your heart beats.

Propafenone is used in certain situations to prevent serious heart rhythm disorders.

Propafenone may also be used for purposes not listed in this medication guide.

Propafenone 225 mg-PAR

capsule, peach/white, imprinted with par 209

Proprafenone 150 mg-ETH

round, white, imprinted with ETH, 331

Proprafenone 225 mg-ETH

round, white, imprinted with 332, ETH

Proprafenone 300 mg-ETH

round, white, imprinted with 333, ETH

Rhythmol SR 225 mg

capsule, white, imprinted with a 225

Rythmol 150 mg

round, white, imprinted with 150 LOGO

Rythmol 225 mg

round, white, imprinted with 225 LOGO

What are the possible side effects of propafenone (Rythmol, Rythmol SR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • chest pain, rapid heart rate, pounding heartbeats or fluttering in your chest;
  • fever, chills, sore throat, flu symptoms, weakness;
  • confusion, unusual thoughts or behavior;
  • seizure; or
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious side effects may include:

  • dizziness, anxiety, loss of balance or coordination;
  • unusual or unpleasant taste in your mouth;
  • nausea, vomiting, constipation, loss of appetite;
  • warmth, redness, or tingly feeling under your skin;
  • headache;
  • tired feeling;
  • ringing in your ears;
  • unusual dreams; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about propafenone (Rythmol, Rythmol SR)?

You should not use this medication if you are allergic to propafenone, or if you have untreated or uncontrolled congestive heart failure, a heart condition called "sick sinus syndrome" or "AV block" (unless you have a pacemaker), slow heartbeats or severely low blood pressure, an electrolyte imbalance, or a breathing disorder such as asthma.

Before you take propafenone, tell your doctor if you have congestive heart failure, liver or kidney disease, lupus, arthritis, myasthenia gravis, or if you have had a heart attack within the past 2 years.

Call your doctor at once if you have a serious side effect such as weak pulse, slow breathing, feeling like you might pass out, feeling short of breath, swelling, rapid weight gain, pale skin, easy bruising or bleeding, unusual weakness, confusion, unusual thoughts or behavior, or seizure.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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