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Prussian blue (cont.)

What should I discuss with my health care provider before taking Prussian blue (Radiogardase)?

Before you take Prussian blue, tell your doctor if you are allergic to any drugs, or if you have:

  • a digestive disorder;
  • chronic constipation;
  • a blockage in your stomach or intestines;
  • a heart rhythm disorder; or
  • an electrolyte imbalance.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use Prussian blue.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant before you are treated with Prussian blue.

It is not known whether Prussian blue passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Exposure to radiation could cause a man to have low sperm counts up to several years later. Talk with your doctor if you have concerns about how radiation may affect your fertility.

How should I take Prussian blue (Radiogardase)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Prussian blue may work best if you take it with food.

Prussian blue is usually taken 3 times per day for at least 30 days. You may need to take several capsules at one time to get the correct dose.

If you are unable to swallow large number of capsules, you may open the capsules and sprinkle the medicine into a small amount of liquid or bland food to make swallowing easier. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

Opening a Prussian blue capsule and mixing the medicine with liquid or food may cause a blue discoloration inside your mouth.

After you are treated with Prussian blue, your urine and stools will contain the radioactive materials that the medication has helped the body eliminate.

Use a toilet rather than a urinal and sit on the toilet while urinating. Flush the toilet 3 times with the lid down after use.

Always wash your hands after using the bathroom.

Avoid handling any clean-up of your stools or urine without wearing latex rubber gloves. If another person is handling your stools or urine, they should wear gloves, eye protection, and a mask to cover the nose and mouth.

When cleaning any spills of bodily fluid, use only disposable cleaning cloths that can be flushed down a toilet. Ask your doctor or health department how to dispose of any bodily fluid spills that cannot be flushed down a toilet.

Wash any soiled clothing separately from the laundry of other people in your home.

Prussian blue may cause your stools to appear blue in color. This is a normal side effect of Prussian blue, and should not be cause for alarm.

Although Prussian blue helps the body quickly eliminate a radioactive element, this medication will not treat any symptoms of radiation exposure. You will be given other medications to treat complications of radiation exposure, such as bone marrow suppression or severe infection.

To be sure this medication is helping your condition, the radiation levels in your urine and stools will need to be checked often. This will help your doctor determine how long to treat you with Prussian blue. Do not miss any scheduled appointments.

Store Prussian blue capsules in the dark at room temperature.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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