Medications and Drugs
Brand Names: Allerfrim, Allerphed, Altafed, Aphedrid, A-Phedrin, Aprodine, Biofed-PE, Genac, Histafed, Pediatex TD, Tripohist D, Vi-Sudo, Zymine-D
Generic Name: pseudoephedrine and triprolidine (Pronunciation: try PROE li deen and soo doe e FED rin)
What is pseudoephedrine and triprolidine (Allerfrim, Allerphed, Altafed, Aphedrid, A-Phedrin, Aprodine, Biofed-PE, Genac, Histafed, Pediatex TD, Tripohist D, Vi-Sudo, Zymine-D)?
Triprolidine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of pseudoephedrine and triprolidine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.
Pseudoephedrine and triprolidine may also be used for other purposes not listed in this medication guide.
What are the possible side effects of pseudoephedrine and triprolidine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about pseudoephedrine and triprolidine?
Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
Pseudoephedrine and triprolidine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can increase some of the side effects of this medication.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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