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Medications and Drugs

Brand Names: Seroquel, Seroquel XR

Generic Name: quetiapine (Pronunciation: kwe TYE a peen)

What is quetiapine (Seroquel, Seroquel XR)?

Quetiapine is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.

Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old.

Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults.

Extended-release quetiapine (Seroquel XR) is for use only in adults and should not be given to anyone younger than 18 years old.

Quetiapine may also be used for purposes not listed in this medication guide.

Quetiapine 100 mg-APO

round, yellow, imprinted with APO, QUE 100

Quetiapine 200 mg-APO

round, white, imprinted with APO, QUE 200

Quetiapine 25 mg-APO

round, pink, imprinted with APO, QUE 25

Quetiapine 300 mg-APO

capsule, white, imprinted with APO, QUE 300

Quetiapine 400 mg-APO

capsule, yellow, imprinted with APO, QUE 400

Quetiapine 50 mg-APO

round, white, imprinted with APO, QUE 50

Seroquel 100 mg

round, yellow, imprinted with SEROQUEL 100

Seroquel 200 mg

round, white, imprinted with SEROQUEL 200

Seroquel 25 mg

round, peach, imprinted with SEROQUEL 25

Seroquel 300 mg

oblong, white, imprinted with SEROQUEL, 300

Seroquel 400 mg

oblong, yellow, imprinted with SEROQUEL, 400

Seroquel 50 mg

round, white, imprinted with SEROQUEL 50

What are the possible side effects of quetiapine (Seroquel, Seroquel XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Stop using quetiapine and call your doctor at once if you have a serious side effect such as:

  • very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors;
  • feeling like you might pass out;
  • jerky muscle movements you cannot control, trouble swallowing, problems with speech;
  • tremors, or restless muscle movements in your eyes, tongue, jaw, neck, arms, or legs;
  • mask-like appearance of the face, trouble swallowing, problems with speech;
  • blurred vision, eye pain, or seeing halos around lights;
  • increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting; or
  • fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips.

Less serious side effects may include:

  • dizziness, drowsiness, tired feeling;
  • dry mouth, sore throat;
  • stomach pain, upset stomach, nausea, vomiting, constipation;
  • breast swelling or discharge;
  • missed menstrual periods; or
  • increased appetite, weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about quetiapine (Seroquel, Seroquel XR)?

Never take quetiapine in larger amounts, or for longer than recommended by your doctor. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include tremors or other uncontrollable muscle movements.

Quetiapine is not for use in psychotic conditions related to dementia. Quetiapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Stop using quetiapine and call your doctor at once if you have the following symptoms: very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, uncontrolled muscle movements, feeling light-headed, blurred vision, eye pain, increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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