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What should I discuss with my healthcare provider before taking rifabutin (Mycobutin)?
You should not take this medication if you are allergic to rifabutin, rifapentine (Priftin), or rifampin (Rifadin, Rifater, Rimactane, Rifamate).
Rifabutin should not be used without other antibiotics to prevent mycobacterium avium complex (MAC) infection in people with active tuberculosis. The tuberculosis may become resistant to treatment if rifabutin is used as a single medication. Be sure to take all your medications as prescribed by your doctor.
Before using rifabutin, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need a dose adjustment or special tests to safely take rifabutin. Your doctor will tell you if any of your medication doses need to be changed.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Rifabutin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking rifabutin.
It is not known whether rifabutin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Rifabutin may cause a red-orange discoloration of breast milk.
How should I take rifabutin (Mycobutin)?
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
You may take rifabutin with or without food. Take the medication with food if it causes stomach upset, nausea, or vomiting.
Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
Store rifabutin at room temperature away from moisture and heat. Keep the bottle tightly closed.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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