Medications and Drugs
Brand Names: Xifaxan
Generic Name: rifaximin (Pronunciation: rif AX i min)
What is rifaximin (Xifaxan)?
Rifaximin is an antibiotic that fights bacterial infection only in the intestines.
Rifaximin works differently from other antibiotics because it passes through your stomach and into your intestines without being absorbed into your blood stream. Because rifaximin treats only the intestinal tract, it will not treat infections of other parts of the body.
Rifaximin is used to treat travelers' diarrhea caused by E. coli in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the bacteria.
Rifaximin is also used to lower the risk of worsened brain function, or hepatic encephalopathy (he-PAT-ik en-SEF-a-LOP-ath-ee), in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.
Rifaximin may also be used for other purposes not listed in this medication guide.
Xifaxan 200 mg
round, brown, imprinted with XS
What are the possible side effects of rifaximin (Xifaxan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using rifaximin and call your doctor at once if you have a fever or diarrhea that is watery or bloody.
Less serious side effects are more likely, and may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about rifaximin (Xifaxan)?
Rifaximin works differently from other antibiotics because it passes through your stomach and into your intestines without being absorbed into your blood stream. Because rifaximin affects only the intestinal tract, it will not treat infections of other parts of the body.
Before you take rifaximin, tell your doctor if you have severe liver disease, diarrhea with fever, or diarrhea that is watery or has blood in it.
Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Rifaximin will not treat a viral infection such as the common cold or flu, or any form of diarrhea that is caused by a virus.
Call your doctor if your symptoms do not improve after 24 hours, or if they get worse while taking rifaximin. Rifaximin does not treat all bacterial forms of traveler's diarrhea.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Find out what women really need.