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What should I discuss with my healthcare provider before using rilonacept (Arcalyst)?
You should not use this medication if you are allergic to rilonacept, or if you have any type of infection.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using rilonacept, tell your doctor if you have a history of tuberculosis.
FDA pregnancy category C. Rilonacept may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether rilonacept passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not use this medication in a child younger than 12 years old unless your doctor has told you to.
How should I use rilonacept (Arcalyst)?
Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Rilonacept is given as an injection under the skin of your stomach, thigh, or upper arm. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
Rilonacept is usually given to adults in two injections at a time, each on a different place on your body. The two injections are then given once per week.
Children may be given one or two injections at a time once per week. Follow your doctor's instructions.
Do not use this medication more often than once per week unless your doctor has told you to.
You will need to mix rilonacept with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication. After mixing rilonacept with a diluent, you must use it within 3 hours.
Each vial (bottle) of rilonacept is for a single use only. Throw the vial away after one use, even if there is still medication left in it.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Do not miss any follow-up visits to your doctor for blood or urine tests.
Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.
Store the unmixed powder medicine in the refrigerator and protected from light. Do not freeze. Keep each vial in the original container until you are ready to mix your medicine.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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