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Medications and Drugs

Brand Names: Edurant

Generic Name: rilpivirine (Pronunciation: RIL pi VIR een)

What is rilpivirine (Edurant)?

Rilpivirine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

Rilpivirine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Rilpivirine is not a cure for HIV or AIDS.

Do not take rilpivirine as your only HIV medication. Rilpivirine must be used in combination with other HIV medicines that your doctor has prescribed.

Rilpivirine may also be used for purposes not listed in this medication guide.

What are the possible side effects of rilpivirine (Edurant)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • mood changes, anxiety, severe depression, feeling hopeless, thoughts about suicide or hurting yourself;
  • fever, chills, cough with yellow or green mucus;
  • stabbing chest pain, wheezing, feeling short of breath; or
  • severe pain in your upper stomach spreading to your shoulder or back, stomach bloating, nausea and vomiting, sweating, fever, chills, loss of appetite.

Less serious side effects may include:

  • sleep problems (insomnia), unusual dreams;
  • mild nausea, vomiting, stomach pain, diarrhea;
  • headache, dizziness;
  • mild skin rash;
  • tired feeling; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about rilpivirine (Edurant)?

There are many other medicines that can interact with rilpivirine, or make it less effective. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Before you take rilpivirine, tell your doctor if you have liver disease (including hepatitis B or C), kidney disease, a history of depression or mental illness, or if you have ever taken any HIV medication in the past.

Do not take rilpivirine as your only HIV medication. HIV/AIDS is usually treated with a combination of different drugs. Your disease may become resistant to rilpivirine if you do not take it in combination with other HIV medicines your doctor has prescribed.

Call your doctor at once if you have mood changes, anxiety, severe depression, feeling hopeless, or thoughts about suicide or hurting yourself.

Taking this medication will not prevent you from passing HIV to other people.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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