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What should I discuss with my healthcare provider before taking rivaroxaban (Xarelto)?
You should not use this medication if you are allergic to rivaroxaban, or if you have active or uncontrolled bleeding.
Rivaroxaban can cause a very serious blood clot around your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if you have:
Rivaroxaban may cause you to bleed more easily, especially if you have:
To make sure you can safely take rivaroxaban, tell your doctor if you have kidney or liver disease.
FDA pregnancy category C. It is not known whether rivaroxaban will harm an unborn baby. However, this medicine could cause bleeding complications during childbirth. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether rivaroxaban passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using rivaroxaban.
How should I take rivaroxaban (Xarelto)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Rivaroxaban is usually taken once per day. Follow your doctor's instructions.
For hip or knee replacement surgery: You may take rivaroxaban with or without food.
For atrial fibrillation: Take rivaroxaban with your evening meal.
Tell any doctor who treats you that you are using rivaroxaban. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using this medication. If you need anesthesia for a medical procedure or surgery, you may need to stop using rivaroxaban for a short time.
Use rivaroxaban regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Do not stop taking this medication without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.
Store at room temperature away from moisture and heat.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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