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What should I discuss with my healthcare provider before taking rivaroxaban (Xarelto)?

You should not use this medication if you are allergic to rivaroxaban, or if you have active or uncontrolled bleeding.

• a genetic spinal defect;
• a history of spinal surgery or repeated spinal taps; or
• if you are using other medications to treat or prevent blood clots.

Rivaroxaban may cause you to bleed more easily, especially if you have:

• a bleeding disorder that is inherited or caused by disease;
• hemorrhagic stroke;
• uncontrolled high blood pressure; or
• stomach or intestinal bleeding or ulcer.

To make sure you can safely take rivaroxaban, tell your doctor if you have kidney or liver disease.

FDA pregnancy category C. It is not known whether rivaroxaban will harm an unborn baby. However, this medicine could cause bleeding complications during childbirth. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether rivaroxaban passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using rivaroxaban.

How should I take rivaroxaban (Xarelto)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

You may take rivaroxaban with or without food. The 20-milligram dose should be taken with food.

Tell any doctor who treats you that you are using rivaroxaban. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using this medication. If you need anesthesia for a medical procedure or surgery, you may need to stop using rivaroxaban for a short time.

Do not stop taking this medication without first talking to your doctor.

Store at room temperature away from moisture and heat.

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