Medications and Drugs
Brand Names: Istodax
Generic Name: romidepsin (Pronunciation: ROE mi DEP sin)
What is romidepsin (Istodax)?
Romidepsin blocks certain enzymes in the body and interferes with the growth of tumor cells.
Romidepsin is used to treat T-cell lymphoma affecting the skin (cutaneous T-cell lymphoma, or CTCL).
Romidepsin is usually given after other medications have been tried without successful treatment of symptoms.
Romidepsin may also be used for other purposes not listed in this medication guide.
What are the possible side effects of romidepsin (Istodax)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about romidepsin (Istodax)?
Do not receive romidepsin if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Hormonal forms of contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking romidepsin.
You will need regular medical tests to be sure this medication is not causing harmful effects. Do not miss any follow-up visits to your doctor.
Call your doctor if you have a serious side effect such as severe nausea or vomiting, chest pain, fast or uneven heartbeats, feeling short of breath, fever, chills, flu symptoms, pale skin, easy bruising or bleeding, muscle cramps, confusion, pain or burning when you urinate, or worsening of your CTCL skin symptoms.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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