rosiglitazone (oral) (cont.)
What happens if I miss a dose (Avandia)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Avandia)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, trouble speaking, blurred vision, nausea, fainting, and seizure (convulsions).
What should I avoid while taking rosiglitazone (Avandia)?
Avoid drinking alcohol. It can lower your blood sugar.
What other drugs will affect rosiglitazone (Avandia)?
You may be more likely to have hyperglycemia (high blood sugar) if you take rosiglitazone with other drugs that can raise blood sugar, such as:
- diuretics (water pills);
- steroids (prednisone and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others); and
- diet pills or medicines to treat asthma, colds, or allergies.
You may be more likely to have hypoglycemia (low blood sugar) if you take rosiglitazone with other drugs that can lower blood sugar, such as:
- probenecid (Benemid);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- a blood thinner (warfarin, Coumadin, Jantoven, and others);
- sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);
- a monoamine oxidase inhibitor (MAOI); or
- other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or other drugs that contain rosiglitazone (Avandaryl, Avandamet).
Some medications may interact with rosiglitazone. Tell your doctor if you are using any of the following drugs:
- delavirdine (Rescriptor);
- gemfibrozil (Lopid);
- nicardipine (Cardene);
- tolbutamide (Orinase);
- antifungal medications such as fluconazole (Diflucan), ketoconazole (Nizoral), or miconazole (Oravig);
- pain or arthritis medicine such as flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), mefenamic acid (Ponstel), or piroxicam (Feldene);
- antibiotics such as rifampin (Rifater, Rifadin, Rifamate) or sulfisoxazole (Pediazole, and others); or
- seizure medicine such as carbamazepine (Carbatrol, Equetro, Tegretol) or phenobarbital (Solfoton).
This list is not complete and other drugs may interact with rosiglitazone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist has additional information about rosiglitazone written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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