Medications and Drugs
Brand Names: Invirase
Generic Name: saquinavir (Pronunciation: sa KWIN a veer)
What is saquinavir (Invirase)?
Saquinavir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Saquinavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Saquinavir is not a cure for HIV or AIDS.
Saquinavir may also be used for purposes not listed in this medication guide.
Invirase 500 mg
oblong, orange, imprinted with SQV 500, ROCHE
What are the possible side effects of saquinavir (Invirase)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about saquinavir (Invirase)?
Saquinavir must be taken together with another medication called ritonavir (Norvir).
You should not take this medication if you are allergic to saquinavir or ritonavir (Norvir, Kaletra).
Life-threatening side effects may occur if you take saquinavir with alfuzosin (Uroxatral), amiodarone (Cordarone, Pacerone), cisapride (Propulsid), dofetilide (Tikosyn), flecainide (Tambocor), lidocaine, lovastatin (Mevacor, Altoprev, Advicor), midazolam (Versed), pimozide (Orap), propafenone (Rythmol), quinidine (Quin-G), rifampin (Rifater, Rifadin, Rifamate), sildenafil (Revatio, for treating pulmonary arterial hypertension), simvastatin (Zocor, Simcor, Vytorin, Juvisync), trazodone (Desyrel), triazolam (Halcion), or an ergot medicine such as Ergomar, Cafergot, Ergotrate, Migranal, or Methergine.
Many other drugs can interact with saquinavir. Tell your doctor about all medications you use. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Resources for Staying Well
- HIV-AIDS: Myths and Facts
- Understanding The Symptoms of AIDS/HIV
- The Top 10 Myths About HIV and AIDS
- How Well Are You Living With AFib?
- How Well Are You Managing Your MS?
- Soothe Your Child's Cold or Flu