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What happens if I miss a dose (Xyrem)?

Take the missed dose as soon as you remember, but only at bedtime or during your normal sleeping hours. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Xyrem)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme sleepiness or confusion, fainting, vomiting, sweating, difficulty breathing, muscle weakness, slow heartbeat, or seizure (convulsions).

What should I avoid while taking sodium oxybate (Xyrem)?

Sodium oxybate must not be taken with other drugs that are used for sleep or sedation.

Drinking alcohol can increase drowsiness and dizziness caused by sodium oxybate.

Sodium oxybate may impair your thinking or reactions. Do not drive, operate machinery, or perform other hazardous activities for at least 6 hours after taking sodium oxybate. You may still feel sleepy the morning after taking the medication. Use caution when driving or doing anything else that requires you to be alert and awake.

What other drugs will affect sodium oxybate (Xyrem)?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by sodium oxybate. Tell your doctor if you regularly use any of these medicines.

This list is not complete and other drugs may interact with sodium oxybate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about sodium oxybate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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