Medications and Drugs
Brand Names: Nexavar
Generic Name: sorafenib (Pronunciation: sor a FEN ib)
What is sorafenib (Nexavar)?
Sorafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Sorafenib is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer.
Sorafenib may also be used for purposes not listed in this medication guide.
What are the possible side effects of sorafenib (Nexavar)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using sorafenib and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about sorafenib (Nexavar)?
Do not use sorafenib if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 2 weeks after your treatment ends, whether you are a man or a woman. Sorafenib use by either parent may cause birth defects.
Do not breast-feed while using this medication.
Before you take sorafenib, tell your doctor if you have kidney or liver problems (other than cancer), a bleeding or blood clotting disorder, high blood pressure, heart disease, slow heartbeats, congestive heart failure, a personal or family history of Long QT syndrome, a history of stroke or heart attack, or any allergies.
There are many other drugs that can interact with sorafenib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are taking sorafenib.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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