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What should I discuss with my healthcare provider before using streptozocin (Zanosar)?

Do not use streptozocin without first talking to your doctor if you have

• kidney disease;
• liver problems;
• bleeding or blood clotting problems; or
• poor bone marrow function.

The use of streptozocin may be dangerous if you have any of the conditions listed above.

Streptozocin is in the FDA pregnancy category D. This means that streptozocin is known to be harmful to an unborn baby. Do not use streptozocin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with streptozocin if necessary.

It is not known whether streptozocin passes into breast milk. Breast-feeding should be avoided during treatment with streptozocin.

How should I use streptozocin (Zanosar)?

Streptozocin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with streptozocin, depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Streptozocin is usually administered as an intravenous (into a vein) injection.

Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with streptozocin to monitor progress and side effects.

Your healthcare provider will store streptozocin as directed by the manufacturer. If you are storing streptozocin at home, follow the directions provided by your healthcare provider.

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