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Medications and Drugs

Brand Names: Klaron, Mexar, Ovace, Ovace Plus, RE 10, Sebizon, Seb-Prev

Generic Name: sulfacetamide sodium topical (Pronunciation: SUL fa SEET a mide SOE dee um TOP i kal)

What is sulfacetamide sodium topical (Klaron, Mexar, Ovace, Ovace Plus, RE 10, Sebizon, Seb-Prev)?

Sulfacetamide sodium is an antibiotic that fights bacteria on the skin.

Sulfacetamide sodium topical (for the skin) is used to treat acne, dandruff, seborrheic dermatitis (red, flaking skin rash), and certain skin infections.

Sulfacetamide sodium topical may also be used for purposes not listed in this medication guide.

What are the possible side effects of sulfacetamide sodium topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • patchy skin color, red spots, a butterfly-shaped skin rash over your cheeks and nose;
  • the first sign of any skin rash, no matter how mild;
  • joint pain, swelling, or stiffness;
  • signs of infection such as fever, sore throat, mouth sores, unusual weakness;
  • pale skin, easy bruising or bleeding;
  • new or worsening skin infection;
  • nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • mild swelling, itching, or redness of treated skin;
  • dry skin; or
  • yellow discoloration of treated skin (may be a sign that you have applied too much of the medication).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about sulfacetamide sodium topical?

You should not use this medication if you are allergic to sulfacetamide sodium or sulfa drugs.

Before using this medication, tell your doctor if you have lupus, asthma or a sulfite allergy, or if you are also using silver sulfadiazine (Silvadene, Thermazene).

Do not use sulfacetamide sodium topical over large skin areas.

Stop using this medication and call your doctor if your symptoms do not improve or if they get worse during treatment.

Avoid getting this medication in your nose, mouth, or eyes.

Stop using sulfacetamide sodium topical and call your doctor at once if you have any type of skin rash (mild or severe), joint pain or swelling, fever or sore throat, mouth sores, pale skin, easy bruising or bleeding, unusual weakness, a new or worsening infection, or stomach pain with loss of appetite, dark urine, clay-colored stools, and jaundice (yellowing of the skin or eyes).



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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