Medications and Drugs

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Brand Names: Clinoril

Generic Name: sulindac (Pronunciation: sul IN dak)

• What is sulindac (Clinoril)?
• What are the possible side effects of sulindac (Clinoril)?
• What is the most important information I should know about sulindac (Clinoril)?
• What should I discuss with my healthcare provider before taking sulindac (Clinoril)?
• How should I take sulindac (Clinoril)?
• What happens if I miss a dose (Clinoril)?
• What happens if I overdose (Clinoril)?
• What should I avoid while taking sulindac (Clinoril)?
• What other drugs will affect sulindac (Clinoril)?
• Where can I get more information?

What is sulindac (Clinoril)?

Sulindac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Sulindac works by reducing hormones that cause inflammation and pain in the body.

Sulindac is used to treat pain or inflammation caused by arthritis, ankylosing spondylitis, tendinitis, bursitis, or gout.

Sulindac may also be used for purposes not listed in this medication guide.

Clinoril 150 mg

hexagonal, yellow, imprinted with MSD 941, CLINORIL

Sulindac 150 mg-MUT

round, yellow, imprinted with MP 112

Sulindac 150 mg-MYL

round, yellow, imprinted with 427, MYLAN

Sulindac 150 mg-SCH

round, yellow, imprinted with 5661, DAN

Sulindac 150 mg-WAT

round, yellow, imprinted with 5661, DAN

Sulindac 200 mg-MUT

round, yellow, imprinted with MP 116

Sulindac 200 mg-MYL

round, yellow, imprinted with MYLAN 531

Sulindac 200 mg-SCH

round, yellow, imprinted with DAN DAN, 5660

Sulindac 200 mg-WAT

round, yellow, imprinted with DAN DAN, 5660

What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sulindac and call your doctor at once if you have a serious side effect such as:

• chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
• black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• urinating less than usual or not at all;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects may include:

• upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;
• dizziness, headache, nervousness;
• skin itching or rash;
• dry mouth;
• increased sweating, runny nose;
• blurred vision; or
• ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about sulindac (Clinoril)?

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use sulindac just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking sulindac, especially in older adults.

Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

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