sumatriptan and naproxen (cont.)
What happens if I miss a dose (Treximet)?
Since sumatriptan and naproxen is taken only when needed, it does not have a daily dosing schedule. Do not take more than 2 sumatriptan and naproxen tablets in 24 hours.
What happens if I overdose (Treximet)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include dizziness, drowsiness, heartburn, stomach pain, nausea, vomiting, breathing problems, black or bloody stools, coughing up blood, and seizure (convulsions).
What should I avoid while taking sumatriptan and naproxen (Treximet)?
Ask a doctor or pharmacist before using any other over-the-counter cold, allergy, or pain medicine. Many combination medicines contain medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking certain products together can cause you to get too much of this type of medicine. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, or naproxen.
Avoid drinking alcohol. It may increase your risk of stomach bleeding caused by naproxen.
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect sumatriptan and naproxen (Treximet)?
Many drugs can interact with sumatriptan and naproxen. Below is just a partial list. Tell your doctor if you are using:
- a blood thinner such as warfarin (Coumadin, Jantoven);
- lithium (Eskalith, Lithobid);
- methotrexate (Rheumatrex, Trexall);
- probenecid (Benemid);
- a diuretic (water pill) such as furosemide (Lasix);
- steroids (prednisone and others);
- aspirin or other NSAIDs such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others;
- heart or blood pressure medication such as atenolol (Tenormin, Tenoretic), benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), metoprolol (Dutoprol, Lopressor, Toprol), propranolol (Inderal, InnoPran), quinapril (Accupril), and others; or
- an antidepressant such as citalopram (Celexa), desvenlafaxine (Pristiq), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).
This list is not complete and other drugs may interact with sumatriptan and naproxen. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about sumatriptan and naproxen.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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