temozolomide (oral) (cont.)
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What should I discuss with my healthcare provider before taking temozolomide (Temodar)?
You should not take this medication if you are allergic to temozolomide or to another cancer medication called dacarbazine (DTIC-Dome).
To make sure you can safely take temozolomide, tell your doctor if you have any of these other conditions:
It is not known whether temozolomide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Taking temozolomide may increase your risk of developing certain types of bone marrow cancer. Talk with your doctor about your individual risk.
Women and older adults may be more likely to have bone marrow suppression (a weakened immune system) while taking temozolomide. This can lead to an increased risk of infection or illness.
How should I take temozolomide (Temodar)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Take temozolomide on an empty stomach, at least 1 hour before or 2 hours after a meal.
Swallow the temozolomide capsule whole, with a full glass of water.
If you vomit shortly after taking temozolomide, do not take another capsule until it is time for your next regularly scheduled dose.
Do not open the temozolomide capsule, or use a pill that has been accidentally broken. The medicine from a crushed or broken pill can be dangerous if you accidentally inhale it, or if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water. Ask your doctor or pharmacist how to safely handle and dispose of a broken tablet or capsule.
You may be given other medications to prevent infection while you are taking temozolomide. Use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.
Temozolomide can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.
Temozolomide is often given together with radiation treatment, and then continued for several weeks or months after radiation treatment ends. There may be periods of time when you will take temozolomide for only a few days in a row and then wait another 2 to 4 weeks before you start a new treatment cycle and take it again. Follow your doctor's instructions carefully.
Your doctor may occasionally change your dose to make sure you get the best results. The size, color, and number of temozolomide capsules you take may be different from time to time as your doctor adjusts your dose. Be sure you know the correct number of capsules to take and on which days to take them. Contact your doctor or pharmacist if you have any questions.
Store at room temperature away from moisture and heat.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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