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Medications and Drugs

Brand Names: Tyzine Nasal

Generic Name: tetrahydrozoline nasal (Pronunciation: TE tra hye DROZ oh leen)

What is tetrahydrozoline nasal (Tyzine Nasal)?

Tetrahydrozoline is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Tetrahydrozoline nasal is used to treat nasal and sinus congestion.

Tetrahydrozoline nasal may also be used for purposes not listed in this medication guide.

What are the possible side effects of tetrahydrozoline nasal (Tyzine Nasal)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using tetrahydrozoline and call your doctor at once if you have any of these serious side effects:

  • severe burning, stinging, redness, or swelling of your nose;
  • fast or pounding heartbeats; or
  • tremors, uncontrolled shaking.

Less serious side effects may include:

  • runny or stuffy nose;
  • sneezing;
  • headache;
  • drowsiness;
  • sleep problems (insomnia); or
  • headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about tetrahydrozoline nasal (Tyzine Nasal)?

Do not use tetrahydrozoline nasal if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before using tetrahydrozoline nasal, tell your doctor if you are allergic to any drugs, or if you have heart disease, coronary artery disease, high blood pressure, diabetes, or a thyroid disorder.

The adult dose of this medication (0.1% nasal spray) should not be used in a child younger than 6 years old. The child's dose (0.05% pediatric drops) should not be used in a child younger than 2 years old.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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