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Medications and Drugs

Brand Names: Tabloid

Generic Name: thioguanine (Pronunciation: THYE oh GWA neen)

What is thioguanine (Tabloid)?

Thioguanine is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Thioguanine is used to treat certain types of leukemia. Thioguanine is sometimes given with other cancer medications.

Thioguanine may also be used for purposes not listed in this medication guide.

What are the possible side effects of thioguanine (Tabloid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using thioguanine and call your doctor at once if you have any of these serious side effects:

  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • fever, chills, body aches, flu symptoms, sores or white patches in your mouth and throat;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • severe vomiting, ongoing diarrhea;
  • severe pain in your upper stomach spreading to your back, fast heart rate;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • vomiting, mild diarrhea;
  • hair loss;
  • mild itching or skin rash; or
  • darkened skin color.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about thioguanine (Tabloid)?

Do not use thioguanine if you are pregnant. It could harm the unborn baby.

You should not use thioguanine if you are allergic to it, or if you have ever used thioguanine or mercaptopurine (Purinethol) and they were not effective in treating your condition.

Before taking thioguanine, tell your doctor if you have liver or kidney disease, or any type of infection.

Stop taking this medication and call your doctor at once if you have easy bruising or bleeding, fever, flu symptoms, mouth sores, dark urine, upper stomach pain, jaundice (yellowing of the skin or eyes), or ongoing diarrhea.

Thioguanine can lower blood cells that help your body fight infections. Your blood cells, kidney function, and liver function may need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow up visits to your doctor for blood or urine tests.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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