Medications and Drugs

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Brand Names: Ticlid

Generic Name: ticlopidine (oral) (Pronunciation: tye KLOE pi deen)

• What is ticlopidine (Ticlid)?
• What are the possible side effects of ticlopidine (Ticlid)?
• What is the most important information I should know about ticlopidine (Ticlid)?
• What should I discuss with my healthcare provider before taking ticlopidine (Ticlid)?
• How should I take ticlopidine (Ticlid)?
• What happens if I miss a dose (Ticlid)?
• What happens if I overdose (Ticlid)?
• What should I avoid while taking ticlopidine (Ticlid)?
• What other drugs will affect ticlopidine (Ticlid)?
• Where can I get more information?

What is ticlopidine (Ticlid)?

Ticlopidine keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions.

Ticlopidine is used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.

Ticlopidine may also be used for other purposes not listed in this medication guide.

Ticlid 250 mg

elliptical, white, imprinted with TICLID, 250

Ticlodipine 250 mg-APO

oblong, white, imprinted with APO 027

Ticlopidine 250 mg-TEV

oval, white, imprinted with 93, 154

What are the possible side effects of ticlopidine (Ticlid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using ticlopidine and call your doctor at once if you have a serious side effect such as:

• nosebleed or other bleeding that will not stop;
• black, bloody, or tarry stools;
• coughing up blood or vomit that looks like coffee grounds;
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance; or
• pale skin, easy bruising or bleeding, weakness, fever, and urinating more or less than usual;
• signs of infection such as fever, chills, sore throat, flu symptoms, mouth sores; or
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• upset stomach, nausea, or vomiting;
• ringing in your ears;
• diarrhea;
• dizziness; or
• itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ticlopidine (Ticlid)?

You should not use this medication if you are allergic to ticlopidine, or if you have severe liver disease, any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury), or a blood cell disorder such as anemia (lack of red blood cells) or low levels of platelets (cells that help your blood clot).

Before taking ticlopidine, tell your doctor if you have a bleeding or blood clotting disorder, a history of stroke, including TIA ("mini-stroke"), a stomach ulcer or ulcerative colitis, high cholesterol or triglycerides, liver disease, or kidney disease.

Because ticlopidine keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using ticlopidine.

While you are taking ticlopidine, do not take aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin) without your doctor's advice.

Taking ticlopidine with certain other drugs can increase your risk of bleeding. Before taking ticlopidine, tell your doctor about all other medications you use.