What happens if I miss a dose (Aptivus)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Aptivus)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking tipranavir (Aptivus)?
If you also take didanosine, take it 2 hours before or after you take tipranavir.
Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
What other drugs will affect tipranavir (Aptivus)?
Many drugs can interact with tipranavir. Below is just a partial list. Tell your doctor if you are using:
- a blood thinner such as warfarin (Coumadin, Jantoven);
- colchicine (Colcrys);
- fluticasone (Advair, Flonase, Flovent);
- insulin or diabetes medication you take by mouth;
- itraconazole (Sporanox) or ketoconazole (Nizoral);
- methadone (Methadose, Diskets, Dolophine);
- omeprazole (Prilosec);
- rifabutin (Mycobutin);
- rosuvastatin (Crestor);
- salmeterol (Advair, Serevent);
- vitamin E (especially at high doses);
- an antidepressant such as desipramine (Norpramin), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), trazodone (Desyrel), and others;
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan);
- drugs that weaken the immune system, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
- medication used to prevent blood clots, such as clopidogrel (Plavix), dipyridamole (Persantine), and others;
- medicines to treat erectile dysfunction, such as Viagra, Cialis or Levitra;
- other HIV /AIDS medicine such as atazanavir (Reyataz), enfuvirtide (Fuzeon), fosamprenavir (Lexiva), lopinavir (Kaletra), raltegravir (Isentress), or saquinavir (Invirase); or
- seizure medications such as carbamazepine (Carbatrol, Tegretol), clonazepam (Klonopin), divalproex (Depakote), ethosuximide (Zarontin), lamotrigine (Lamictal), phenobarbital (Solfoton), phenytoin (Dilantin), or valproic acid (Depakene).
This list is not complete and there are many other drugs that can interact with tipranavir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about tipranavir.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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